Showing posts with label Vitamin A. Show all posts
Showing posts with label Vitamin A. Show all posts

Monday, October 18, 2010

Vitamin A Pill Could Protect Millions From Going Blind

Researchers have discovered a vitamin A based drug that could prevent millions from going blind as they age. During old age trials, researchers behind the drug fenretinide, found the treatment halted the advance of age-related macular degeneration, the most common cause of blindness, and for which there is no cure, currently.

They targeted dry AMD, the most prevalent form of the condition caused by the deterioration and death of cells in the macula, a part of the retina used for seeing straight ahead. Creating a black spot in the centre of their vision, the disease causes many sufferers to lose their sight.

As well, it makes everyday tasks like reading, driving and watching television impossible to carry out.

While, it is possible to treat the wet form of the disease that is not so common, there is nothing that can be done for the majority of patients.

American researchers in their study of fenretinide derived from vitamin A to be found in carrots, and designed to tackle arthritis, originally, gave a fenretinide pill or a placebo to 250 men and women with dry AMD, participating in the study, every day.

After a year, the highest dose drug halted visual deterioration, and while it could not do anything about damaged cells that were dying, it was able to protect health cells from deteriorating.

The research offers promise of a treatment for the disease, even though it is still in its preliminary stage, offering hope to the 300,000 Britons suffering from the disease. If, further trials are successful the drug could become available within 5 years.

Macular degeneration affects millions worldwide, and the numbers of those suffering from it in the UK could treble to one million as the population ages, within 25 years.

Via : visitbulgaria

Vitamin A drug 'could save eyesight'


Doctors believe that fenretinide can halt the advance of macular degeneration - a disease for which there is currently no cure.

Researchers have discovered that the drug can help stop "dry" AMD which is caused by the destruction of cells in macula, the part of the retina which allows you to see straight ahead.

"Dry" AMD is the most prevalent form of the disease and leaves a black spot in sufferers' vision.

In a US study Fenretinide, which is derived from vitamin A, was given to 250 people with "dry" AMD. It was found to halt the deterioration of eyesight by protecting healthy cells but not stopping the destruction of of cells that were already damaged.

It gives hope to the 300,000 Britons who suffer from the disease.

Dr Jason Slakter, of New York University School of Medicine, said: "There are currently no effective treatments for dry AMN and the need for finding one is grave.

"Our study wasn't designed to give a final answer. It was designed to see if there was a biological effect and if the drug was working in the way we'd expect and to find out if it was well tolerated by patients.

"I think we answered all of these points favourably."

If further trials are succesful the drug could become available within 5 years.

Via : telegraph